STRINGSTRING
TSPAN12 protein (Canis lupus) - STRING interaction network
"TSPAN12" - Tetraspanin 12 in Canis lupus
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TSPAN12Tetraspanin 12 (305 aa)    
Predicted Functional Partners:
NDP
NDP, norrin cystine knot growth factor; Norrie disease (pseudoglioma) (133 aa)
       
 
  0.919
FZD4
Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family (528 aa)
     
 
  0.831
LRP5
Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor- ligand complexes into ribosome-sized signalsomes (1614 aa)
     
 
  0.800
ZNF408
Zinc finger protein 408 (752 aa)
           
  0.754
TSPAN17
Tetraspanin 17 (281 aa)
           
  0.739
TSPAN15
Tetraspanin 15 (294 aa)
     
   
  0.697
LDLR
Low density lipoprotein receptor (861 aa)
       
 
  0.640
KIF11
Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family (1052 aa)
           
  0.605
LGR4
Leucine-rich repeat containing G protein-coupled receptor 4 (905 aa)
     
   
  0.570
LGR6
Leucine-rich repeat containing G protein-coupled receptor 6 (965 aa)
     
   
  0.564
Your Current Organism:
Canis lupus
NCBI taxonomy Id: 9612
Other names: C. lupus, Canis familiaris, Canis lupus, gray wolf, grey wolf
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