STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLC7A11Cystine/glutamate exchanger. (527 aa)    
Predicted Functional Partners:
SLC3A2
Aamy domain-containing protein.
   
 0.997
ACSL4
Acyl-CoA synthetase long chain family member 4.
   
  
 0.714
SLC3A1
Solute carrier family 3 member 1.
   
 
 0.675
CD44
CD44 antigen.
   
 
 0.668
SLC1A5
Amino acid transporter.
   
 
 0.579
ACSF2
Acyl-CoA synthetase family member 2.
      
 0.560
ZKSCAN8
Zinc finger with KRAB and SCAN domains 8.
    
 
 0.552
GLS2
Glutaminase 2.
  
  
 0.550
ZBTB41
Zinc finger and BTB domain containing 41.
   
 
 0.548
SACS
Sacsin molecular chaperone.
    
 
 0.535
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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