STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMEM135Transmembrane protein 135. (458 aa)    
Predicted Functional Partners:
PXMP4
Peroxisomal membrane protein 4; Belongs to the peroxisomal membrane protein PXMP2/4 family.
   
  
 0.795
CCDC170
Coiled-coil domain containing 170.
      
 0.751
GPATCH1
G-patch domain containing 1.
   
  
 0.669
FAM167A
Family with sequence similarity 167 member A.
      
 0.662
SEPTIN5
Septin 5; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
      
 0.654
ACAT2
Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.
   
  
 0.615
MAN2A1
Alpha-mannosidase.
   
  
 0.607
ZBTB40
Zinc finger and BTB domain containing 40.
      
 0.577
MTFP1
Mitochondrial fission process 1.
      
 0.574
PXMP2
Peroxisomal membrane protein 2; Belongs to the peroxisomal membrane protein PXMP2/4 family.
   
  
 0.565
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.