STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OTOP3Otopetrin 3. (571 aa)    
Predicted Functional Partners:
RGR
Retinal G protein coupled receptor; Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
   
  
 0.730
NR2C1
Nuclear receptor subfamily 2 group C member 1.
   
  
 0.695
TCTA
T-cell leukemia translocation-altered gene protein homolog; May be required for cellular fusion during osteoclastogenesis; Belongs to the TCTA family.
      
 0.653
OLFM1
Olfactomedin 1.
      
 0.619
RARRES2
Retinoic acid receptor responder 2.
      
 0.525
PDE8B
Phosphodiesterase 8B; Belongs to the cyclic nucleotide phosphodiesterase family.
      
 0.515
NUPR1
Nuclear protein 1, transcriptional regulator.
      
 0.515
PDE8A
Phosphodiesterase.
      
 0.515
FDXR
NADPH:adrenodoxin oxidoreductase, mitochondrial.
   
  
 0.513
RNF157
Ring finger protein 157.
      
 0.503
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.