STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GAAGlucosidase alpha, acid. (1187 aa)    
Predicted Functional Partners:
CCDC114
Coiled-coil domain containing 114.
   
  
 0.929
CCDC39
Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly.
    
 
 0.913
CCDC103
Coiled-coil domain containing 103.
      
 0.880
DNAH11
Dynein axonemal heavy chain 11.
   
 
 0.873
DNAI2
Dynein axonemal intermediate chain 2.
      
 0.868
RSPH9
Radial spoke head 9 homolog.
   
  
 0.864
CCDC65
Coiled-coil domain containing 65.
   
 
 0.861
RSPH4A
Radial spoke head component 4A.
   
 
 0.836
TTC29
Tetratricopeptide repeat domain 29.
   
 
 0.830
AK7
Adenylate kinase 7.
   
 
 0.821
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.