STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRPF40APre-mRNA processing factor 40 homolog A. (994 aa)    
Predicted Functional Partners:
RBM25
RNA binding motif protein 25.
   
 0.959
RBM39
RNA binding motif protein 39.
   
  0.899
SRRM1
PWI domain-containing protein.
   
 0.897
SF1
Splicing factor 1.
   
 0.893
TCERG1
Transcription elongation regulator 1.
   
0.879
NIF3L1
NIF3-like protein 1; May function as a transcriptional corepressor through its interaction with COPS2, negatively regulating the expression of genes involved in neuronal differentiation.
   
  
 0.867
KLHL30
Kelch like family member 30.
    
 
 0.863
MTREX
Mtr4 exosome RNA helicase.
   
  0.859
DDX5
Uncharacterized protein; Belongs to the DEAD box helicase family.
   
 0.849
DHX9
DExH-box helicase 9.
   
 0.840
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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