STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OSBPOxysterol-binding protein; Belongs to the OSBP family. (773 aa)    
Predicted Functional Partners:
VAPA
VAMP associated protein A.
    
 
 0.979
VAPB
VAMP associated protein B and C.
   
 
 0.875
PLEK2
Pleckstrin 2.
   
  
 0.803
PLEK
Pleckstrin; Major protein kinase C substrate of platelets.
   
  
 0.794
SPHKAP
SPHK1 interactor, AKAP domain containing.
   
  
 0.681
ESYT1
Extended synaptotagmin 1.
   
 
 0.666
PGAM1
PI3K/PI4K domain-containing protein.
      
 0.666
ACBD3
Acyl-CoA binding domain containing 3.
   
  
 0.657
ARFIP2
ADP ribosylation factor interacting protein 2.
   
  
 0.631
CNDP1
Carnosine dipeptidase 1.
   
  
 0.612
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.