STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BLKTyrosine-protein kinase. (500 aa)    
Predicted Functional Partners:
FAM167A
Family with sequence similarity 167 member A.
   
 
 0.832
ZNF831
Zinc finger protein 831.
    
 
 0.777
CD19
CD19 molecule.
   
 
 0.757
FAM189A2
Family with sequence similarity 189 member A2.
   
 
 0.750
DNASE2B
Deoxyribonuclease 2 beta.
   
  
 0.744
FCRLA
Fc receptor like A.
   
 
 0.730
SOWAHA
Sosondowah ankyrin repeat domain family member A.
    
 
 0.725
SULT1C3
Sulfotransferase; Belongs to the sulfotransferase 1 family.
   
  
 0.716
ZNF512
Zinc finger protein 512.
    
 
 0.699
ANKRD22
Ankyrin repeat domain 22.
   
 
 0.684
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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