STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TOX2TOX high mobility group box family member 2. (616 aa)    
Predicted Functional Partners:
ARHGEF3
Rho guanine nucleotide exchange factor 3.
    
 
 0.748
DAPP1
Dual adaptor of phosphotyrosine and 3-phosphoinositides 1.
   
 
 0.738
NDFIP2
Nedd4 family interacting protein 2.
      
 0.650
PDE4A
Phosphodiesterase.
      
 0.650
SH2B3
SH2B adaptor protein 3.
      
 0.598
ASB2
Ankyrin repeat and SOCS box containing 2.
    
 
 0.582
ZMAT1
Zinc finger matrin-type 1.
   
  
 0.520
RERE
Arginine-glutamic acid dipeptide repeats.
      
 0.517
IBTK
Inhibitor of Bruton tyrosine kinase.
   
  
 0.507
ZNF516
Zinc finger protein 516.
    
 
 0.502
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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