node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ESRRA | ESRRB | ENSCAFP00000021334 | ENSCAFP00000050405 | Steroid hormone receptor ERR1; Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium- chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. May function as a modulator of the estrogen signaling pathway in the uterus. Induces the expression of PERM1 in the skeletal muscle (By similarity). Belongs to the nuclear hormone receptor family. NR3 subfamily. | Estrogen related receptor beta. | 0.630 |
ESRRA | ESRRG | ENSCAFP00000021334 | ENSCAFP00000037484 | Steroid hormone receptor ERR1; Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium- chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. May function as a modulator of the estrogen signaling pathway in the uterus. Induces the expression of PERM1 in the skeletal muscle (By similarity). Belongs to the nuclear hormone receptor family. NR3 subfamily. | Estrogen related receptor gamma. | 0.587 |
ESRRA | MED1 | ENSCAFP00000021334 | ENSCAFP00000024203 | Steroid hormone receptor ERR1; Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium- chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. May function as a modulator of the estrogen signaling pathway in the uterus. Induces the expression of PERM1 in the skeletal muscle (By similarity). Belongs to the nuclear hormone receptor family. NR3 subfamily. | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.588 |
ESRRA | NCOR1 | ENSCAFP00000021334 | ENSCAFP00000053648 | Steroid hormone receptor ERR1; Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium- chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. May function as a modulator of the estrogen signaling pathway in the uterus. Induces the expression of PERM1 in the skeletal muscle (By similarity). Belongs to the nuclear hormone receptor family. NR3 subfamily. | Nuclear receptor corepressor 1. | 0.820 |
ESRRA | NCOR2 | ENSCAFP00000021334 | ENSCAFP00000010374 | Steroid hormone receptor ERR1; Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium- chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. May function as a modulator of the estrogen signaling pathway in the uterus. Induces the expression of PERM1 in the skeletal muscle (By similarity). Belongs to the nuclear hormone receptor family. NR3 subfamily. | Nuclear receptor corepressor 2. | 0.638 |
ESRRA | NRF1 | ENSCAFP00000021334 | ENSCAFP00000044920 | Steroid hormone receptor ERR1; Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium- chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. May function as a modulator of the estrogen signaling pathway in the uterus. Induces the expression of PERM1 in the skeletal muscle (By similarity). Belongs to the nuclear hormone receptor family. NR3 subfamily. | Nuclear respiratory factor 1. | 0.597 |
ESRRA | NRIP1 | ENSCAFP00000021334 | ENSCAFP00000011935 | Steroid hormone receptor ERR1; Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium- chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. May function as a modulator of the estrogen signaling pathway in the uterus. Induces the expression of PERM1 in the skeletal muscle (By similarity). Belongs to the nuclear hormone receptor family. NR3 subfamily. | Nuclear receptor interacting protein 1. | 0.606 |
ESRRA | PPARGC1A | ENSCAFP00000021334 | ENSCAFP00000050517 | Steroid hormone receptor ERR1; Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium- chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. May function as a modulator of the estrogen signaling pathway in the uterus. Induces the expression of PERM1 in the skeletal muscle (By similarity). Belongs to the nuclear hormone receptor family. NR3 subfamily. | PPARG coactivator 1 alpha. | 0.979 |
ESRRA | PPARGC1B | ENSCAFP00000021334 | ENSCAFP00000052080 | Steroid hormone receptor ERR1; Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium- chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. May function as a modulator of the estrogen signaling pathway in the uterus. Induces the expression of PERM1 in the skeletal muscle (By similarity). Belongs to the nuclear hormone receptor family. NR3 subfamily. | PPARG coactivator 1 beta. | 0.662 |
ESRRA | TFAM | ENSCAFP00000021334 | ENSCAFP00000033819 | Steroid hormone receptor ERR1; Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium- chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. May function as a modulator of the estrogen signaling pathway in the uterus. Induces the expression of PERM1 in the skeletal muscle (By similarity). Belongs to the nuclear hormone receptor family. NR3 subfamily. | Transcription factor A, mitochondrial. | 0.623 |
ESRRB | ESRRA | ENSCAFP00000050405 | ENSCAFP00000021334 | Estrogen related receptor beta. | Steroid hormone receptor ERR1; Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium- chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. May function as a modulator of the estrogen signaling pathway in the uterus. Induces the expression of PERM1 in the skeletal muscle (By similarity). Belongs to the nuclear hormone receptor family. NR3 subfamily. | 0.630 |
ESRRB | ESRRG | ENSCAFP00000050405 | ENSCAFP00000037484 | Estrogen related receptor beta. | Estrogen related receptor gamma. | 0.458 |
ESRRB | MED1 | ENSCAFP00000050405 | ENSCAFP00000024203 | Estrogen related receptor beta. | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.556 |
ESRRB | NCOR1 | ENSCAFP00000050405 | ENSCAFP00000053648 | Estrogen related receptor beta. | Nuclear receptor corepressor 1. | 0.653 |
ESRRB | NCOR2 | ENSCAFP00000050405 | ENSCAFP00000010374 | Estrogen related receptor beta. | Nuclear receptor corepressor 2. | 0.760 |
ESRRB | NRIP1 | ENSCAFP00000050405 | ENSCAFP00000011935 | Estrogen related receptor beta. | Nuclear receptor interacting protein 1. | 0.615 |
ESRRB | PPARGC1A | ENSCAFP00000050405 | ENSCAFP00000050517 | Estrogen related receptor beta. | PPARG coactivator 1 alpha. | 0.632 |
ESRRG | ESRRA | ENSCAFP00000037484 | ENSCAFP00000021334 | Estrogen related receptor gamma. | Steroid hormone receptor ERR1; Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium- chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. May function as a modulator of the estrogen signaling pathway in the uterus. Induces the expression of PERM1 in the skeletal muscle (By similarity). Belongs to the nuclear hormone receptor family. NR3 subfamily. | 0.587 |
ESRRG | ESRRB | ENSCAFP00000037484 | ENSCAFP00000050405 | Estrogen related receptor gamma. | Estrogen related receptor beta. | 0.458 |
ESRRG | MED1 | ENSCAFP00000037484 | ENSCAFP00000024203 | Estrogen related receptor gamma. | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.556 |