PAX3 protein (Canis lupus familiaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

PAX3

Paired box 3. (514 aa)

Predicted Functional Partners:

MYF5

0.932

SOX10

0.931

NCOA1

0.916

PAX7

0.916

MYOG

0.900

MYOD1

0.812

FOXD3

0.728

MYF6

0.700

TIMM22

0.672

FOXO1

0.666

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FOXD3	PAX3	ENSCAFP00000020261	ENSCAFP00000023626	Forkhead box D3.	Paired box 3.	0.728
FOXD3	SOX10	ENSCAFP00000020261	ENSCAFP00000002067	Forkhead box D3.	SRY-box transcription factor 10.	0.725
FOXO1	MYF5	ENSCAFP00000008944	ENSCAFP00000008695	Forkhead box O1.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.440
FOXO1	MYOD1	ENSCAFP00000008944	ENSCAFP00000013332	Forkhead box O1.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.564
FOXO1	MYOG	ENSCAFP00000008944	ENSCAFP00000015142	Forkhead box O1.	Myogenin.	0.592
FOXO1	PAX3	ENSCAFP00000008944	ENSCAFP00000023626	Forkhead box O1.	Paired box 3.	0.666
FOXO1	PAX7	ENSCAFP00000008944	ENSCAFP00000022903	Forkhead box O1.	Paired box 7.	0.626
MYF5	FOXO1	ENSCAFP00000008695	ENSCAFP00000008944	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	Forkhead box O1.	0.440
MYF5	MYF6	ENSCAFP00000008695	ENSCAFP00000008676	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	Myogenic factor 6.	0.690
MYF5	MYOD1	ENSCAFP00000008695	ENSCAFP00000013332	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.422
MYF5	MYOG	ENSCAFP00000008695	ENSCAFP00000015142	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	Myogenin.	0.669
MYF5	PAX3	ENSCAFP00000008695	ENSCAFP00000023626	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	Paired box 3.	0.932
MYF5	PAX7	ENSCAFP00000008695	ENSCAFP00000022903	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	Paired box 7.	0.940
MYF6	MYF5	ENSCAFP00000008676	ENSCAFP00000008695	Myogenic factor 6.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.690
MYF6	MYOD1	ENSCAFP00000008676	ENSCAFP00000013332	Myogenic factor 6.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.667
MYF6	MYOG	ENSCAFP00000008676	ENSCAFP00000015142	Myogenic factor 6.	Myogenin.	0.650
MYF6	PAX3	ENSCAFP00000008676	ENSCAFP00000023626	Myogenic factor 6.	Paired box 3.	0.700
MYF6	PAX7	ENSCAFP00000008676	ENSCAFP00000022903	Myogenic factor 6.	Paired box 7.	0.793
MYOD1	FOXO1	ENSCAFP00000013332	ENSCAFP00000008944	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	Forkhead box O1.	0.564
MYOD1	MYF5	ENSCAFP00000013332	ENSCAFP00000008695	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.422