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ARHGAP17 protein (Canis lupus) - STRING interaction network
"ARHGAP17" - Rho GTPase activating protein 17 in Canis lupus
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ARHGAP17Rho GTPase activating protein 17 (918 aa)    
Predicted Functional Partners:
ENSCAFG00000012631
Uncharacterized protein; Belongs to the small GTPase superfamily. Rho family (179 aa)
     
  0.930
RHOA
Transforming protein RhoA; Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Involved in a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Plays an essential role in cleavage furrow formation. Required for the apical junction formation of keratinocyte cell-cell adhesion. May be an activator of PLCE1. Activated by ARHGEF2, which promotes the exchange of GDP for GTP. Essential for the SPATA13-mediated regulation of cell migration and a [...] (193 aa)
     
  0.923
RHOC
Ras homolog family member C; Belongs to the small GTPase superfamily. Rho family (205 aa)
     
  0.921
RAC1
Ras-related C3 botulinum toxin substrate 1; Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization and growth-factor induced formation of membrane ruffles. Rac1 p21/rho GDI heterodimer is the active component of the cytosolic factor sigma 1, which is involved in stimulation of the NADPH oxidase activity in macrophages. Essential for the SPATA13-mediated [...] (211 aa)
     
  0.920
RAC2
Ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2); Belongs to the small GTPase superfamily. Rho family (192 aa)
     
  0.920
RHOB
Uncharacterized protein; Ras homolog family member B; Belongs to the small GTPase superfamily. Rho family (196 aa)
     
  0.920
RHOH
Ras homolog family member H; Belongs to the small GTPase superfamily. Rho family (191 aa)
     
  0.919
RHOU
Ras homolog family member U; Belongs to the small GTPase superfamily. Rho family (258 aa)
     
  0.918
RHOQ
Uncharacterized protein; Ras homolog family member Q; Belongs to the small GTPase superfamily. Rho family (126 aa)
     
  0.918
RHOV
Ras homolog family member V; Belongs to the small GTPase superfamily. Rho family (236 aa)
     
  0.917
Your Current Organism:
Canis lupus
NCBI taxonomy Id: 9612
Other names: C. lupus, Canis familiaris, Canis lupus, gray wolf, grey wolf
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