STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
COL4A5Collagen alpha-5(IV) chain; Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. (1691 aa)    
Predicted Functional Partners:
COL4A2
Collagen type IV alpha 2 chain.
  
 
0.934
COL4A6
Collagen type IV alpha 6 chain.
  
0.912
GP6
Glycoprotein VI platelet.
     
 0.907
ITGA3
Integrin subunit alpha 3; Belongs to the integrin alpha chain family.
    
 0.854
PELO
Integrin subunit alpha 1; Belongs to the integrin alpha chain family.
   
 0.851
ITGB4
Integrin beta.
   
 0.823
ITGA2
Integrin subunit alpha 2; Belongs to the integrin alpha chain family.
    
 0.768
ITGA8
Integrin subunit alpha 8; Belongs to the integrin alpha chain family.
   
 0.752
ITGA5
Integrin subunit alpha 5; Belongs to the integrin alpha chain family.
   
 0.742
ITGA6
Integrin subunit alpha 6; Belongs to the integrin alpha chain family.
   
 0.741
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.