STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
S1PR4Sphingosine-1-phosphate receptor 4. (383 aa)    
Predicted Functional Partners:
GNAI1
G protein subunit alpha i1.
 
  
 0.932
GNAI3
G protein subunit alpha i3.
 
  
 0.932
GNAI2
Guanine nucleotide-binding protein G(i) subunit alpha-2; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta- adrenergic stimuli. May play a role in cell division (By similarity).
 
 
 0.932
GNA12
G protein subunit alpha 12.
 
 
 0.931
GNA13
G protein subunit alpha 13.
 
  
 0.923
S1PR1
Sphingosine-1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family.
   
 
 
0.900
OR2W1
Olfactory receptor.
      
 0.803
S1PR2
Sphingosine-1-phosphate receptor 2; Belongs to the G-protein coupled receptor 1 family.
   
0.570
OR3A1
Olfactory receptor.
      
 0.560
S1PR5
Sphingosine-1-phosphate receptor 5.
  
0.545
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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