STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTATP6ATP synthase subunit a; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] (226 aa)    
Predicted Functional Partners:
ATP5D
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
  
 0.996
ATP5A1
ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane
  
 0.995
ENSCAFG00000017648
ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane
  
 0.995
ATP5B
ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane
  
 0.992
ATP5F1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1
   
 0.992
ENSCAFG00000009682
ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane
  
 0.992
ATP5C1
Uncharacterized protein
  
 0.991
ENSCAFG00000020261
Uncharacterized protein
  
 0.991
MTATP8
ATP synthase protein 8; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...]
   
 
 0.989
MTCO3
Cytochrome c oxidase subunit 3; Subunits I, II and III form the functional core of the enzyme complex
   
 
 0.989
Your Current Organism:
Canis lupus
NCBI taxonomy Id: 9612
Other names: C. lupus, Canis familiaris, Canis lupus, gray wolf, grey wolf
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