node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BCL2L1 | BID | ENSCAFP00000010478 | ENSCAFP00000052515 | BCL2 like 1. | BH3 interacting domain death agonist. | 0.988 |
BCL2L1 | CTSB | ENSCAFP00000010478 | ENSCAFP00000059573 | BCL2 like 1. | Cathepsin B; Belongs to the peptidase C1 family. | 0.909 |
BCL2L1 | CTSD | ENSCAFP00000010478 | ENSCAFP00000014791 | BCL2 like 1. | Cathepsin D; Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation; Belongs to the peptidase A1 family. | 0.904 |
BCL2L1 | CTSH | ENSCAFP00000010478 | ENSCAFP00000031547 | BCL2 like 1. | Cathepsin H; Belongs to the peptidase C1 family. | 0.902 |
BID | BCL2L1 | ENSCAFP00000052515 | ENSCAFP00000010478 | BH3 interacting domain death agonist. | BCL2 like 1. | 0.988 |
BID | CTSB | ENSCAFP00000052515 | ENSCAFP00000059573 | BH3 interacting domain death agonist. | Cathepsin B; Belongs to the peptidase C1 family. | 0.912 |
BID | CTSD | ENSCAFP00000052515 | ENSCAFP00000014791 | BH3 interacting domain death agonist. | Cathepsin D; Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation; Belongs to the peptidase A1 family. | 0.907 |
BID | CTSH | ENSCAFP00000052515 | ENSCAFP00000031547 | BH3 interacting domain death agonist. | Cathepsin H; Belongs to the peptidase C1 family. | 0.904 |
BIRC3 | BIRC5 | ENSCAFP00000050122 | ENSCAFP00000045531 | Baculoviral IAP repeat-containing protein 3; Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling and cell proliferation, as well as cell invasion and metastasis. Acts as an E3 ubiquitin-protein ligase regulating NF-kappa-B signaling and regulates both canonical and non- canonical NF-kappa-B signaling by acting in opposite directions: acts as a positive regulator of the canonical pathway and suppresses constitutive activation of non-canonical NF-kappa-B signaling. The target proteins [...] | Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...] | 0.901 |
BIRC3 | CTSB | ENSCAFP00000050122 | ENSCAFP00000059573 | Baculoviral IAP repeat-containing protein 3; Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling and cell proliferation, as well as cell invasion and metastasis. Acts as an E3 ubiquitin-protein ligase regulating NF-kappa-B signaling and regulates both canonical and non- canonical NF-kappa-B signaling by acting in opposite directions: acts as a positive regulator of the canonical pathway and suppresses constitutive activation of non-canonical NF-kappa-B signaling. The target proteins [...] | Cathepsin B; Belongs to the peptidase C1 family. | 0.666 |
BIRC3 | CTSD | ENSCAFP00000050122 | ENSCAFP00000014791 | Baculoviral IAP repeat-containing protein 3; Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling and cell proliferation, as well as cell invasion and metastasis. Acts as an E3 ubiquitin-protein ligase regulating NF-kappa-B signaling and regulates both canonical and non- canonical NF-kappa-B signaling by acting in opposite directions: acts as a positive regulator of the canonical pathway and suppresses constitutive activation of non-canonical NF-kappa-B signaling. The target proteins [...] | Cathepsin D; Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation; Belongs to the peptidase A1 family. | 0.654 |
BIRC3 | CTSH | ENSCAFP00000050122 | ENSCAFP00000031547 | Baculoviral IAP repeat-containing protein 3; Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling and cell proliferation, as well as cell invasion and metastasis. Acts as an E3 ubiquitin-protein ligase regulating NF-kappa-B signaling and regulates both canonical and non- canonical NF-kappa-B signaling by acting in opposite directions: acts as a positive regulator of the canonical pathway and suppresses constitutive activation of non-canonical NF-kappa-B signaling. The target proteins [...] | Cathepsin H; Belongs to the peptidase C1 family. | 0.664 |
BIRC5 | BIRC3 | ENSCAFP00000045531 | ENSCAFP00000050122 | Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...] | Baculoviral IAP repeat-containing protein 3; Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling and cell proliferation, as well as cell invasion and metastasis. Acts as an E3 ubiquitin-protein ligase regulating NF-kappa-B signaling and regulates both canonical and non- canonical NF-kappa-B signaling by acting in opposite directions: acts as a positive regulator of the canonical pathway and suppresses constitutive activation of non-canonical NF-kappa-B signaling. The target proteins [...] | 0.901 |
BIRC5 | CTSB | ENSCAFP00000045531 | ENSCAFP00000059573 | Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...] | Cathepsin B; Belongs to the peptidase C1 family. | 0.673 |
BIRC5 | CTSD | ENSCAFP00000045531 | ENSCAFP00000014791 | Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...] | Cathepsin D; Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation; Belongs to the peptidase A1 family. | 0.656 |
BIRC5 | CTSH | ENSCAFP00000045531 | ENSCAFP00000031547 | Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...] | Cathepsin H; Belongs to the peptidase C1 family. | 0.668 |
CTSA | CTSB | ENSCAFP00000014432 | ENSCAFP00000059573 | Carboxypeptidase; Belongs to the peptidase S10 family. | Cathepsin B; Belongs to the peptidase C1 family. | 0.840 |
CTSA | CTSD | ENSCAFP00000014432 | ENSCAFP00000014791 | Carboxypeptidase; Belongs to the peptidase S10 family. | Cathepsin D; Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation; Belongs to the peptidase A1 family. | 0.777 |
CTSA | CTSH | ENSCAFP00000014432 | ENSCAFP00000031547 | Carboxypeptidase; Belongs to the peptidase S10 family. | Cathepsin H; Belongs to the peptidase C1 family. | 0.666 |
CTSB | BCL2L1 | ENSCAFP00000059573 | ENSCAFP00000010478 | Cathepsin B; Belongs to the peptidase C1 family. | BCL2 like 1. | 0.909 |