STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ELSPBP1Epididymal sperm-binding protein 1; Binds to spermatozoa upon ejaculation and may play a role in sperm capacitation. Has phosphorylcholine-binding activity (By similarity). (261 aa)    
Predicted Functional Partners:
J9P5V4_CANLF
S_100 domain-containing protein; Belongs to the S-100 family.
    
 
 0.853
TEX101
Testis expressed 101.
   
  
 0.794
LOC611724
Uncharacterized protein; Belongs to the adenylate kinase family.
   
  
 0.786
CABP5
Calcium binding protein 5.
   
  
 0.764
ZNF575
Zinc finger protein 575.
   
  
 0.617
PHLDB3
Pleckstrin homology like domain family B member 3.
      
 0.604
TIMP2
Metalloproteinase inhibitor 2; Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor; Belongs to the protease inhibitor I35 (TIMP) family.
   
 
 0.590
TIMP3
TIMP metallopeptidase inhibitor 3.
   
 
 0.581
ENO4
Enolase 4.
   
  
 0.551
SERPINF2
Serpin family F member 2; Belongs to the serpin family.
   
 
 0.548
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.