STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZBTB7AZinc finger and BTB domain containing 7A. (714 aa)    
Predicted Functional Partners:
KLF12
Kruppel like factor 12.
   
 
 0.654
LZTS1
Leucine zipper tumor suppressor 1.
   
  
 0.644
SRBD1
S1 RNA binding domain 1.
   
 
 0.576
PCBP3
Poly(rC) binding protein 3.
    
 
 0.573
TAF3
TATA-box binding protein associated factor 3.
   
 
 0.560
DCLRE1B
DNA cross-link repair 1B.
   
 
 0.548
HDAC1
Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
    
 
 0.544
HDAC2
Histone deacetylase 2.
    
 
 0.544
NAIF1
Nuclear apoptosis inducing factor 1.
      
 0.525
MAP3K6
Mitogen-activated protein kinase kinase kinase 6.
    
 
 0.521
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.