STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKR1E2Aldo-keto reductase family 1 member E2. (301 aa)    
Predicted Functional Partners:
RDH14
Uncharacterized protein.
   
 
 0.877
WDR87
WD repeat domain 87.
      
 0.809
MFSD6L
Major facilitator superfamily domain containing 6 like.
      
 0.809
SPECC1
Sperm antigen with calponin homology and coiled-coil domains 1.
   
  
 0.808
TAPT1
Transmembrane anterior posterior transformation 1.
      
 0.680
IGF2BP3
Insulin like growth factor 2 mRNA binding protein 3.
   
  
 0.648
RNLS
Renalase, FAD dependent amine oxidase.
      
 0.643
CYP51A1
Cytochrome P450 family 51 subfamily A member 1; Belongs to the cytochrome P450 family.
   
  
 0.591
SIPA1L3
Signal induced proliferation associated 1 like 3.
      
 0.521
GCLC
Glutamate-cysteine ligase catalytic subunit.
   
 0.518
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.