STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FRS3Fibroblast growth factor receptor substrate 3. (496 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor bound protein 2.
    
 0.811
PTPN11
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.
    
 0.763
FGFR1
Fibroblast growth factor receptor.
    
 0.744
FGFR2
Fibroblast growth factor receptor.
    
 0.744
FGFR4
Fibroblast growth factor receptor.
   
 0.709
FGFR3
Fibroblast growth factor receptor 3.
   
 0.706
GHITM
Growth hormone inducible transmembrane protein; Belongs to the BI1 family.
      
 0.676
PPP2R2C
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.
   
 
 0.653
SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1.
   
 0.640
TENM2
Teneurin transmembrane protein 2.
      
 0.619
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.