TNFRSF11A protein (Canis lupus familiaris) - STRING interaction network

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Score

TNFRSF11A

TNF receptor superfamily member 11a. (648 aa)

Predicted Functional Partners:

TNFSF11

0.994

TRAF6

0.974

TRAF2

0.942

RELCH

0.867

TAP1

0.705

TNFSF14

0.678

BIRC3

0.658

LTB

0.656

ZNF687

0.649

TRAF3

0.648

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BIRC3	LTB	ENSCAFP00000050122	ENSCAFP00000039920	Baculoviral IAP repeat-containing protein 3; Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling and cell proliferation, as well as cell invasion and metastasis. Acts as an E3 ubiquitin-protein ligase regulating NF-kappa-B signaling and regulates both canonical and non- canonical NF-kappa-B signaling by acting in opposite directions: acts as a positive regulator of the canonical pathway and suppresses constitutive activation of non-canonical NF-kappa-B signaling. The target proteins [...]	Tumor necrosis factor ligand 1C; Belongs to the tumor necrosis factor family.	0.668
BIRC3	TAP1	ENSCAFP00000050122	ENSCAFP00000064521	Baculoviral IAP repeat-containing protein 3; Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling and cell proliferation, as well as cell invasion and metastasis. Acts as an E3 ubiquitin-protein ligase regulating NF-kappa-B signaling and regulates both canonical and non- canonical NF-kappa-B signaling by acting in opposite directions: acts as a positive regulator of the canonical pathway and suppresses constitutive activation of non-canonical NF-kappa-B signaling. The target proteins [...]	Uncharacterized protein.	0.449
BIRC3	TNFRSF11A	ENSCAFP00000050122	ENSCAFP00000000112	Baculoviral IAP repeat-containing protein 3; Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling and cell proliferation, as well as cell invasion and metastasis. Acts as an E3 ubiquitin-protein ligase regulating NF-kappa-B signaling and regulates both canonical and non- canonical NF-kappa-B signaling by acting in opposite directions: acts as a positive regulator of the canonical pathway and suppresses constitutive activation of non-canonical NF-kappa-B signaling. The target proteins [...]	TNF receptor superfamily member 11a.	0.658
BIRC3	TNFSF11	ENSCAFP00000050122	ENSCAFP00000006955	Baculoviral IAP repeat-containing protein 3; Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling and cell proliferation, as well as cell invasion and metastasis. Acts as an E3 ubiquitin-protein ligase regulating NF-kappa-B signaling and regulates both canonical and non- canonical NF-kappa-B signaling by acting in opposite directions: acts as a positive regulator of the canonical pathway and suppresses constitutive activation of non-canonical NF-kappa-B signaling. The target proteins [...]	TNF superfamily member 11; Belongs to the tumor necrosis factor family.	0.520
BIRC3	TNFSF14	ENSCAFP00000050122	ENSCAFP00000041489	Baculoviral IAP repeat-containing protein 3; Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling and cell proliferation, as well as cell invasion and metastasis. Acts as an E3 ubiquitin-protein ligase regulating NF-kappa-B signaling and regulates both canonical and non- canonical NF-kappa-B signaling by acting in opposite directions: acts as a positive regulator of the canonical pathway and suppresses constitutive activation of non-canonical NF-kappa-B signaling. The target proteins [...]	Tumor necrosis factor ligand 1D; Belongs to the tumor necrosis factor family.	0.671
BIRC3	TRAF2	ENSCAFP00000050122	ENSCAFP00000028895	Baculoviral IAP repeat-containing protein 3; Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling and cell proliferation, as well as cell invasion and metastasis. Acts as an E3 ubiquitin-protein ligase regulating NF-kappa-B signaling and regulates both canonical and non- canonical NF-kappa-B signaling by acting in opposite directions: acts as a positive regulator of the canonical pathway and suppresses constitutive activation of non-canonical NF-kappa-B signaling. The target proteins [...]	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.967
BIRC3	TRAF3	ENSCAFP00000050122	ENSCAFP00000026713	Baculoviral IAP repeat-containing protein 3; Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling and cell proliferation, as well as cell invasion and metastasis. Acts as an E3 ubiquitin-protein ligase regulating NF-kappa-B signaling and regulates both canonical and non- canonical NF-kappa-B signaling by acting in opposite directions: acts as a positive regulator of the canonical pathway and suppresses constitutive activation of non-canonical NF-kappa-B signaling. The target proteins [...]	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.969
BIRC3	TRAF6	ENSCAFP00000050122	ENSCAFP00000010159	Baculoviral IAP repeat-containing protein 3; Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling and cell proliferation, as well as cell invasion and metastasis. Acts as an E3 ubiquitin-protein ligase regulating NF-kappa-B signaling and regulates both canonical and non- canonical NF-kappa-B signaling by acting in opposite directions: acts as a positive regulator of the canonical pathway and suppresses constitutive activation of non-canonical NF-kappa-B signaling. The target proteins [...]	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.661
LTB	BIRC3	ENSCAFP00000039920	ENSCAFP00000050122	Tumor necrosis factor ligand 1C; Belongs to the tumor necrosis factor family.	Baculoviral IAP repeat-containing protein 3; Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling and cell proliferation, as well as cell invasion and metastasis. Acts as an E3 ubiquitin-protein ligase regulating NF-kappa-B signaling and regulates both canonical and non- canonical NF-kappa-B signaling by acting in opposite directions: acts as a positive regulator of the canonical pathway and suppresses constitutive activation of non-canonical NF-kappa-B signaling. The target proteins [...]	0.668
LTB	TAP1	ENSCAFP00000039920	ENSCAFP00000064521	Tumor necrosis factor ligand 1C; Belongs to the tumor necrosis factor family.	Uncharacterized protein.	0.465
LTB	TNFRSF11A	ENSCAFP00000039920	ENSCAFP00000000112	Tumor necrosis factor ligand 1C; Belongs to the tumor necrosis factor family.	TNF receptor superfamily member 11a.	0.656
LTB	TNFSF11	ENSCAFP00000039920	ENSCAFP00000006955	Tumor necrosis factor ligand 1C; Belongs to the tumor necrosis factor family.	TNF superfamily member 11; Belongs to the tumor necrosis factor family.	0.587
LTB	TNFSF14	ENSCAFP00000039920	ENSCAFP00000041489	Tumor necrosis factor ligand 1C; Belongs to the tumor necrosis factor family.	Tumor necrosis factor ligand 1D; Belongs to the tumor necrosis factor family.	0.596
LTB	TRAF2	ENSCAFP00000039920	ENSCAFP00000028895	Tumor necrosis factor ligand 1C; Belongs to the tumor necrosis factor family.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.559
LTB	TRAF3	ENSCAFP00000039920	ENSCAFP00000026713	Tumor necrosis factor ligand 1C; Belongs to the tumor necrosis factor family.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.670
RELCH	TNFRSF11A	ENSCAFP00000054483	ENSCAFP00000000112	RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing.	TNF receptor superfamily member 11a.	0.867
TAP1	BIRC3	ENSCAFP00000064521	ENSCAFP00000050122	Uncharacterized protein.	Baculoviral IAP repeat-containing protein 3; Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling and cell proliferation, as well as cell invasion and metastasis. Acts as an E3 ubiquitin-protein ligase regulating NF-kappa-B signaling and regulates both canonical and non- canonical NF-kappa-B signaling by acting in opposite directions: acts as a positive regulator of the canonical pathway and suppresses constitutive activation of non-canonical NF-kappa-B signaling. The target proteins [...]	0.449
TAP1	LTB	ENSCAFP00000064521	ENSCAFP00000039920	Uncharacterized protein.	Tumor necrosis factor ligand 1C; Belongs to the tumor necrosis factor family.	0.465
TAP1	TNFRSF11A	ENSCAFP00000064521	ENSCAFP00000000112	Uncharacterized protein.	TNF receptor superfamily member 11a.	0.705
TAP1	TNFSF11	ENSCAFP00000064521	ENSCAFP00000006955	Uncharacterized protein.	TNF superfamily member 11; Belongs to the tumor necrosis factor family.	0.400