STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IRAK3Interleukin 1 receptor associated kinase 3. (650 aa)    
Predicted Functional Partners:
IRAK2
Interleukin 1 receptor associated kinase 2.
   
0.961
IRAK4
Interleukin 1 receptor associated kinase 4.
  
 
0.951
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.924
NGFR
Nerve growth factor receptor.
    
 0.909
IRAK1
Interleukin 1 receptor associated kinase 1.
  
 
0.794
MYD88
MYD88 innate immune signal transduction adaptor.
   
 0.726
TOLLIP
Toll interacting protein.
   
 0.674
IL1R1
Interleukin 1 receptor type 1.
   
 0.642
TMBIM4
Uncharacterized protein; Belongs to the BI1 family.
      
 0.634
IL1RAP
Interleukin 1 receptor accessory protein.
   
 0.605
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.