TSPAN8 protein (Canis lupus familiaris) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

TSPAN8

Tetraspanin. (237 aa)

Predicted Functional Partners:

ITGA4

0.693

LGALS2

0.635

ABHD15

0.610

CAPN10

0.565

IGF2BP2

0.552

SDR16C5

0.534

GPRC5B

0.529

TEX36

0.515

ANKS4B

0.513

TM4SF4

0.510

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABHD15	ANKS4B	ENSCAFP00000061657	ENSCAFP00000063298	Abhydrolase domain containing 15.	Ankyrin repeat and sterile alpha motif domain containing 4B.	0.783
ABHD15	TM4SF4	ENSCAFP00000061657	ENSCAFP00000033932	Abhydrolase domain containing 15.	Transmembrane 4 L six family member 4.	0.769
ABHD15	TSPAN8	ENSCAFP00000061657	ENSCAFP00000000667	Abhydrolase domain containing 15.	Tetraspanin.	0.610
ANKS4B	ABHD15	ENSCAFP00000063298	ENSCAFP00000061657	Ankyrin repeat and sterile alpha motif domain containing 4B.	Abhydrolase domain containing 15.	0.783
ANKS4B	TM4SF4	ENSCAFP00000063298	ENSCAFP00000033932	Ankyrin repeat and sterile alpha motif domain containing 4B.	Transmembrane 4 L six family member 4.	0.527
ANKS4B	TSPAN8	ENSCAFP00000063298	ENSCAFP00000000667	Ankyrin repeat and sterile alpha motif domain containing 4B.	Tetraspanin.	0.513
CAPN10	TSPAN8	ENSCAFP00000060396	ENSCAFP00000000667	Calpain 10; Belongs to the peptidase C2 family.	Tetraspanin.	0.565
GPRC5B	LGALS2	ENSCAFP00000026635	ENSCAFP00000052081	G protein-coupled receptor class C group 5 member B.	Galectin.	0.769
GPRC5B	TSPAN8	ENSCAFP00000026635	ENSCAFP00000000667	G protein-coupled receptor class C group 5 member B.	Tetraspanin.	0.529
IGF2BP2	TSPAN8	ENSCAFP00000019639	ENSCAFP00000000667	Insulin like growth factor 2 mRNA binding protein 2.	Tetraspanin.	0.552
ITGA4	TSPAN8	ENSCAFP00000020903	ENSCAFP00000000667	Integrin subunit alpha 4; Belongs to the integrin alpha chain family.	Tetraspanin.	0.693
LGALS2	GPRC5B	ENSCAFP00000052081	ENSCAFP00000026635	Galectin.	G protein-coupled receptor class C group 5 member B.	0.769
LGALS2	TM4SF4	ENSCAFP00000052081	ENSCAFP00000033932	Galectin.	Transmembrane 4 L six family member 4.	0.719
LGALS2	TSPAN8	ENSCAFP00000052081	ENSCAFP00000000667	Galectin.	Tetraspanin.	0.635
SDR16C5	TSPAN8	ENSCAFP00000010491	ENSCAFP00000000667	Short chain dehydrogenase/reductase family 16C member 5; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	Tetraspanin.	0.534
TEX36	TSPAN8	ENSCAFP00000045202	ENSCAFP00000000667	Testis expressed 36.	Tetraspanin.	0.515
TM4SF4	ABHD15	ENSCAFP00000033932	ENSCAFP00000061657	Transmembrane 4 L six family member 4.	Abhydrolase domain containing 15.	0.769
TM4SF4	ANKS4B	ENSCAFP00000033932	ENSCAFP00000063298	Transmembrane 4 L six family member 4.	Ankyrin repeat and sterile alpha motif domain containing 4B.	0.527
TM4SF4	LGALS2	ENSCAFP00000033932	ENSCAFP00000052081	Transmembrane 4 L six family member 4.	Galectin.	0.719
TM4SF4	TSPAN8	ENSCAFP00000033932	ENSCAFP00000000667	Transmembrane 4 L six family member 4.	Tetraspanin.	0.510