STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RNF19ARBR-type E3 ubiquitin transferase. (838 aa)    
Predicted Functional Partners:
TUBGCP3
Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family.
   
  
 0.874
PSMC3
AAA domain-containing protein; Belongs to the AAA ATPase family.
      
 0.873
TUBG1
Tubulin gamma-1 chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation (By similarity).
   
  
 0.867
STK17B
Serine/threonine kinase 17b; Belongs to the protein kinase superfamily.
   
  
 0.656
SCEL
Sciellin.
    
 
 0.579
CELF1
CUGBP Elav-like family member 1.
      
 0.535
FAM167A
Family with sequence similarity 167 member A.
   
  
 0.523
ZNF830
Zinc finger protein 830.
   
  
 0.520
NAA15
N(alpha)-acetyltransferase 15, NatA auxiliary subunit.
      
 0.515
P2RX5
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
      
 0.515
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.