STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TBXTT-box transcription factor T; Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation. Binds to a palindromic site (called T site) and activates gene transcription when bound to such a site. (435 aa)    
Predicted Functional Partners:
SOX17
SRY-box 17.
   
 
 0.521
DNAJB5
DnaJ heat shock protein family (Hsp40) member B5.
   
  
 0.511
FOXA2
Forkhead box A2.
    
 
 0.481
SMARCA4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4.
   
 
 0.466
RIN3
Ras and Rab interactor 3.
      
 0.465
PDGFD
Platelet derived growth factor D.
      
 0.461
NCDN
Neurochondrin.
   
  
 0.459
POU3F1
POU domain protein.
   
 
 0.458
RTL4
Retrotransposon Gag like 4.
      
 0.457
KLF12
Kruppel like factor 12.
    
 
 0.451
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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