STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
HSD17B8Zinc transporter SLC39A7; Zinc transporter, that transports Zn(2+) from the endoplasmic reticulum/Golgi apparatus to the cytosol; Belongs to the ZIP transporter (TC 2.A.5) family. KE4/Catsup subfamily. (638 aa)    
Predicted Functional Partners:
SLC30A9
Solute carrier family 30 member 9.
  
  
 0.788
SEC61A1
Protein transport protein Sec61 subunit alpha isoform 1.
   
  
 0.697
SEC61A2
Protein transport protein Sec61 subunit alpha isoform 1; Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across endoplasmic reticulum (ER). Forms a ribosome receptor and a gated pore in the ER membrane, both functions required for cotranslational translocation of nascent polypeptides. May cooperate with auxiliary protein SEC62, SEC63 and HSPA5/BiP to enable post- translational transport of small presecretory proteins. Controls the passive efflux of calcium ions from the ER lumen to the cytosol through SEC [...]
   
  
 0.695
CLUL1
Clusterin-like protein 1.
      
 0.675
TTC38
Tetratricopeptide repeat domain 38.
   
  
 0.673
SLC39A3
Solute carrier family 39 member 3.
   
 
 0.656
CLIP3
CAP-Gly domain containing linker protein 3.
   
  
 0.651
SLC30A6
Solute carrier family 30 member 6.
  
 
 0.620
OR6K6
Olfactory receptor.
      
 0.591
DHRS9
Dehydrogenase/reductase 9; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
   
 0.591
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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