STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
USP36Ubiquitin specific peptidase 36; Belongs to the peptidase C19 family. (1155 aa)    
Predicted Functional Partners:
ZNF768
Zinc finger protein 768.
      
 0.857
RAPGEF1
Rap guanine nucleotide exchange factor 1.
   
  
 0.848
DNMBP
Dynamin-binding protein; Plays a critical role as a guanine nucleotide exchange factor (GEF) for CDC42 in several intracellular processes associated with the actin and microtubule cytoskeleton. Regulates the structure of apical junctions in epithelial cells (By similarity). Participates in the normal lumenogenesis of epithelial cell cysts by regulating spindle orientation. Plays a key role in ciliogenesis and cyst formation. May play a role in membrane trafficking between the cell surface and the Golgi (By similarity).
      
 0.826
ZNF598
Zinc finger protein 598.
   
  
 0.775
CNTF
Uncharacterized protein.
   
  
 0.690
GPS1
G protein pathway suppressor 1.
      
 0.646
RBBP6
RB binding protein 6, ubiquitin ligase.
   
  
 0.602
FANCI
FA complementation group I.
   
 
 0.595
DHX33
DEAH-box helicase 33.
   
 
 0.594
USP39
Ubiquitin specific peptidase 39.
   
  
0.562
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.