| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMPD2 | GMPR | ENSCAFP00000031117 | ENSCAFP00000014617 | Adenosine monophosphate deaminase 2. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.937 |
| AMPD2 | GMPR2 | ENSCAFP00000031117 | ENSCAFP00000017919 | Adenosine monophosphate deaminase 2. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.937 |
| AMPD2 | NT5C | ENSCAFP00000031117 | ENSCAFP00000035634 | Adenosine monophosphate deaminase 2. | 5', 3'-nucleotidase, cytosolic. | 0.966 |
| AMPD2 | NT5M | ENSCAFP00000031117 | ENSCAFP00000041751 | Adenosine monophosphate deaminase 2. | 5',3'-nucleotidase, mitochondrial. | 0.944 |
| AMPD2 | NUDT16 | ENSCAFP00000031117 | ENSCAFP00000009189 | Adenosine monophosphate deaminase 2. | Nudix hydrolase 16. | 0.903 |
| GMPR | AMPD2 | ENSCAFP00000014617 | ENSCAFP00000031117 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Adenosine monophosphate deaminase 2. | 0.937 |
| GMPR | GMPR2 | ENSCAFP00000014617 | ENSCAFP00000017919 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.928 |
| GMPR | NT5C | ENSCAFP00000014617 | ENSCAFP00000035634 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 5', 3'-nucleotidase, cytosolic. | 0.937 |
| GMPR | NT5M | ENSCAFP00000014617 | ENSCAFP00000041751 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 5',3'-nucleotidase, mitochondrial. | 0.937 |
| GMPR | NUDT16 | ENSCAFP00000014617 | ENSCAFP00000009189 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Nudix hydrolase 16. | 0.913 |
| GMPR2 | AMPD2 | ENSCAFP00000017919 | ENSCAFP00000031117 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Adenosine monophosphate deaminase 2. | 0.937 |
| GMPR2 | GMPR | ENSCAFP00000017919 | ENSCAFP00000014617 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.928 |
| GMPR2 | NT5C | ENSCAFP00000017919 | ENSCAFP00000035634 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 5', 3'-nucleotidase, cytosolic. | 0.938 |
| GMPR2 | NT5M | ENSCAFP00000017919 | ENSCAFP00000041751 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 5',3'-nucleotidase, mitochondrial. | 0.937 |
| GMPR2 | NUDT16 | ENSCAFP00000017919 | ENSCAFP00000009189 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Nudix hydrolase 16. | 0.913 |
| NME1 | NME2 | ENSCAFP00000025500 | ENSCAFP00000025504 | Nucleoside diphosphate kinase A; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3'-5' exonuclease activities. Involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Required for n [...] | Nucleoside diphosphate kinase B; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity). Negatively regulates Rho activity by interacting with AKAP13/LBC. Acts as a transcriptional activator of the MYC gene; binds DNA non-specifically. Binds to both single-stranded guanine- and cytosine-rich strands within the nuclease hypersensitive element (NHE) III(1) region of the MYC gene promoter. Does not bind to duplex NHE I [...] | 0.950 |
| NME1 | NME4 | ENSCAFP00000025500 | ENSCAFP00000029117 | Nucleoside diphosphate kinase A; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3'-5' exonuclease activities. Involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Required for n [...] | NDK domain-containing protein; Belongs to the NDK family. | 0.926 |
| NME1 | NME6 | ENSCAFP00000025500 | ENSCAFP00000049324 | Nucleoside diphosphate kinase A; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3'-5' exonuclease activities. Involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Required for n [...] | Nucleoside diphosphate kinase. | 0.916 |
| NME1 | NME7 | ENSCAFP00000025500 | ENSCAFP00000022471 | Nucleoside diphosphate kinase A; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3'-5' exonuclease activities. Involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Required for n [...] | Nucleoside diphosphate kinase 7; Belongs to the NDK family. | 0.907 |
| NME1 | NUDT16 | ENSCAFP00000025500 | ENSCAFP00000009189 | Nucleoside diphosphate kinase A; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3'-5' exonuclease activities. Involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Required for n [...] | Nudix hydrolase 16. | 0.904 |