MAPKAPK3 protein (Canis lupus familiaris) - STRING interaction network

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Score

MAPKAPK3

MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (381 aa)

Predicted Functional Partners:

HSPB1

0.980

MAPK12

0.970

MAPK13

0.969

MAPK14

0.969

MAPK11

0.969

ATF4

0.902

DCX

0.826

MAP2K3

0.742

ENSCAFP00000054940

0.665

MAP2K6

0.624

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATF4	MAPKAPK3	ENSCAFP00000001900	ENSCAFP00000015096	Activating transcription factor 4.	MAPK activated protein kinase 3; Belongs to the protein kinase superfamily.	0.902
DCX	MAPKAPK3	ENSCAFP00000038521	ENSCAFP00000015096	Doublecortin.	MAPK activated protein kinase 3; Belongs to the protein kinase superfamily.	0.826
ENSCAFP00000054940	MAP2K3	ENSCAFP00000054940	ENSCAFP00000061410	Protein kinase domain-containing protein.	Mitogen-activated protein kinase kinase 3.	0.626
ENSCAFP00000054940	MAP2K6	ENSCAFP00000054940	ENSCAFP00000059059	Protein kinase domain-containing protein.	Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily.	0.911
ENSCAFP00000054940	MAPKAPK3	ENSCAFP00000054940	ENSCAFP00000015096	Protein kinase domain-containing protein.	MAPK activated protein kinase 3; Belongs to the protein kinase superfamily.	0.665
HSPB1	MAPK11	ENSCAFP00000019945	ENSCAFP00000062533	Heat shock protein beta-1; Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding- competent state. Plays a role in stress resistance and actin organization. Through its molecular chaperone activity may regulate numerous biological processes including the phosphorylation and the axonal transport of neurofilament proteins.	Mitogen-activated protein kinase.	0.666
HSPB1	MAPK13	ENSCAFP00000019945	ENSCAFP00000001972	Heat shock protein beta-1; Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding- competent state. Plays a role in stress resistance and actin organization. Through its molecular chaperone activity may regulate numerous biological processes including the phosphorylation and the axonal transport of neurofilament proteins.	Mitogen-activated protein kinase.	0.477
HSPB1	MAPK14	ENSCAFP00000019945	ENSCAFP00000048255	Heat shock protein beta-1; Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding- competent state. Plays a role in stress resistance and actin organization. Through its molecular chaperone activity may regulate numerous biological processes including the phosphorylation and the axonal transport of neurofilament proteins.	Mitogen-activated protein kinase 14; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK14 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. Some of the targets are downstream kinases which are a [...]	0.674
HSPB1	MAPKAPK3	ENSCAFP00000019945	ENSCAFP00000015096	Heat shock protein beta-1; Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding- competent state. Plays a role in stress resistance and actin organization. Through its molecular chaperone activity may regulate numerous biological processes including the phosphorylation and the axonal transport of neurofilament proteins.	MAPK activated protein kinase 3; Belongs to the protein kinase superfamily.	0.980
MAP2K3	ENSCAFP00000054940	ENSCAFP00000061410	ENSCAFP00000054940	Mitogen-activated protein kinase kinase 3.	Protein kinase domain-containing protein.	0.626
MAP2K3	MAP2K6	ENSCAFP00000061410	ENSCAFP00000059059	Mitogen-activated protein kinase kinase 3.	Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily.	0.901
MAP2K3	MAPK11	ENSCAFP00000061410	ENSCAFP00000062533	Mitogen-activated protein kinase kinase 3.	Mitogen-activated protein kinase.	0.965
MAP2K3	MAPK12	ENSCAFP00000061410	ENSCAFP00000000978	Mitogen-activated protein kinase kinase 3.	Mitogen-activated protein kinase.	0.962
MAP2K3	MAPK13	ENSCAFP00000061410	ENSCAFP00000001972	Mitogen-activated protein kinase kinase 3.	Mitogen-activated protein kinase.	0.965
MAP2K3	MAPK14	ENSCAFP00000061410	ENSCAFP00000048255	Mitogen-activated protein kinase kinase 3.	Mitogen-activated protein kinase 14; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK14 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. Some of the targets are downstream kinases which are a [...]	0.965
MAP2K3	MAPKAPK3	ENSCAFP00000061410	ENSCAFP00000015096	Mitogen-activated protein kinase kinase 3.	MAPK activated protein kinase 3; Belongs to the protein kinase superfamily.	0.742
MAP2K6	ENSCAFP00000054940	ENSCAFP00000059059	ENSCAFP00000054940	Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein.	0.911
MAP2K6	MAP2K3	ENSCAFP00000059059	ENSCAFP00000061410	Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase kinase 3.	0.901
MAP2K6	MAPK11	ENSCAFP00000059059	ENSCAFP00000062533	Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase.	0.991
MAP2K6	MAPK12	ENSCAFP00000059059	ENSCAFP00000000978	Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase.	0.968