node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GNAI1 | GNAI2 | ENSCAFP00000024156 | ENSCAFP00000033576 | G protein subunit alpha i1. | Guanine nucleotide-binding protein G(i) subunit alpha-2; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta- adrenergic stimuli. May play a role in cell division (By similarity). | 0.901 |
GNAI1 | GNAI3 | ENSCAFP00000024156 | ENSCAFP00000029356 | G protein subunit alpha i1. | G protein subunit alpha i3. | 0.902 |
GNAI1 | GNB1 | ENSCAFP00000024156 | ENSCAFP00000028342 | G protein subunit alpha i1. | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.956 |
GNAI1 | GNB2 | ENSCAFP00000024156 | ENSCAFP00000033929 | G protein subunit alpha i1. | G protein subunit beta 2. | 0.884 |
GNAI1 | GNB3 | ENSCAFP00000024156 | ENSCAFP00000058821 | G protein subunit alpha i1. | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.858 |
GNAI1 | GNB4 | ENSCAFP00000024156 | ENSCAFP00000016683 | G protein subunit alpha i1. | G protein subunit beta 4. | 0.956 |
GNAI1 | GNB5 | ENSCAFP00000024156 | ENSCAFP00000023022 | G protein subunit alpha i1. | G protein subunit beta 5. | 0.826 |
GNAI1 | PTGER1 | ENSCAFP00000024156 | ENSCAFP00000024002 | G protein subunit alpha i1. | Prostaglandin E2 receptor EP1 subtype; Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(q) proteins which activate a phosphatidylinositol-calcium second messenger system. May play a role as an important modulator of renal function. Implicated the smooth muscle contractile response to PGE2 in various tissues (By similarity). Belongs to the G-protein coupled receptor 1 family. | 0.908 |
GNAI1 | PTGER2 | ENSCAFP00000024156 | ENSCAFP00000021671 | G protein subunit alpha i1. | Prostaglandin E2 receptor EP2 subtype; Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. The subsequent raise in intracellular cAMP is responsible for the relaxing effect of this receptor on smooth muscle (By similarity). Belongs to the G-protein coupled receptor 1 family. | 0.908 |
GNAI1 | PTGER4 | ENSCAFP00000024156 | ENSCAFP00000046114 | G protein subunit alpha i1. | Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. | 0.914 |
GNAI2 | GNAI1 | ENSCAFP00000033576 | ENSCAFP00000024156 | Guanine nucleotide-binding protein G(i) subunit alpha-2; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta- adrenergic stimuli. May play a role in cell division (By similarity). | G protein subunit alpha i1. | 0.901 |
GNAI2 | GNAI3 | ENSCAFP00000033576 | ENSCAFP00000029356 | Guanine nucleotide-binding protein G(i) subunit alpha-2; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta- adrenergic stimuli. May play a role in cell division (By similarity). | G protein subunit alpha i3. | 0.901 |
GNAI2 | GNB1 | ENSCAFP00000033576 | ENSCAFP00000028342 | Guanine nucleotide-binding protein G(i) subunit alpha-2; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta- adrenergic stimuli. May play a role in cell division (By similarity). | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.956 |
GNAI2 | GNB2 | ENSCAFP00000033576 | ENSCAFP00000033929 | Guanine nucleotide-binding protein G(i) subunit alpha-2; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta- adrenergic stimuli. May play a role in cell division (By similarity). | G protein subunit beta 2. | 0.907 |
GNAI2 | GNB3 | ENSCAFP00000033576 | ENSCAFP00000058821 | Guanine nucleotide-binding protein G(i) subunit alpha-2; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta- adrenergic stimuli. May play a role in cell division (By similarity). | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.858 |
GNAI2 | GNB4 | ENSCAFP00000033576 | ENSCAFP00000016683 | Guanine nucleotide-binding protein G(i) subunit alpha-2; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta- adrenergic stimuli. May play a role in cell division (By similarity). | G protein subunit beta 4. | 0.956 |
GNAI2 | GNB5 | ENSCAFP00000033576 | ENSCAFP00000023022 | Guanine nucleotide-binding protein G(i) subunit alpha-2; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta- adrenergic stimuli. May play a role in cell division (By similarity). | G protein subunit beta 5. | 0.826 |
GNAI2 | PTGER1 | ENSCAFP00000033576 | ENSCAFP00000024002 | Guanine nucleotide-binding protein G(i) subunit alpha-2; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta- adrenergic stimuli. May play a role in cell division (By similarity). | Prostaglandin E2 receptor EP1 subtype; Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(q) proteins which activate a phosphatidylinositol-calcium second messenger system. May play a role as an important modulator of renal function. Implicated the smooth muscle contractile response to PGE2 in various tissues (By similarity). Belongs to the G-protein coupled receptor 1 family. | 0.908 |
GNAI2 | PTGER2 | ENSCAFP00000033576 | ENSCAFP00000021671 | Guanine nucleotide-binding protein G(i) subunit alpha-2; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta- adrenergic stimuli. May play a role in cell division (By similarity). | Prostaglandin E2 receptor EP2 subtype; Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. The subsequent raise in intracellular cAMP is responsible for the relaxing effect of this receptor on smooth muscle (By similarity). Belongs to the G-protein coupled receptor 1 family. | 0.908 |
GNAI2 | PTGER4 | ENSCAFP00000033576 | ENSCAFP00000046114 | Guanine nucleotide-binding protein G(i) subunit alpha-2; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta- adrenergic stimuli. May play a role in cell division (By similarity). | Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. | 0.914 |