STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPAG1Uncharacterized protein. (447 aa)    
Predicted Functional Partners:
DNAAF5
Dynein axonemal assembly factor 5.
      
 0.929
DNAAF3
Dynein axonemal assembly factor 3.
      
 0.870
RSPH1
Radial spoke head 1 homolog.
   
 
 0.851
PIH1D2
PIH1 domain containing 2.
   
 
 0.844
RSPH9
Radial spoke head 9 homolog.
   
 
 0.834
ZMYND10
Zinc finger MYND domain-containing protein 10; Plays a role in axonemal structure organization and motility. Involved in axonemal pre-assembly of inner and outer dynein arms (IDA and ODA, respectively) for proper axoneme building for cilia motility. May act by indirectly regulating transcription of dynein proteins. Belongs to the ZMYND10 family.
   
  
 0.823
CCDC103
Coiled-coil domain containing 103.
      
 0.818
LRRC6
Leucine rich repeat containing 6.
   
 
 0.802
RSPH4A
Radial spoke head component 4A.
   
 
 0.791
NME8
NME/NM23 family member 8.
  
 0.779
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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