STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VIL1Villin 1. (865 aa)    
Predicted Functional Partners:
ASCL2
Achaete-scute family bHLH transcription factor 2.
   
  
 0.656
TM4SF4
Transmembrane 4 L six family member 4.
   
  
 0.606
CHGB
Chromogranin B.
   
 
 0.573
PDF
Conserved oligomeric Golgi complex subunit 8; Belongs to the COG8 family.
    
 
 0.552
LGR5
Leucine rich repeat containing G protein-coupled receptor 5.
    
 
 0.529
RUFY4
RUN and FYVE domain containing 4.
    
 
 0.519
CDH17
Cadherin 17.
   
  
 0.509
COG6
Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.
    
 
 0.508
COG4
Component of oligomeric golgi complex 4.
   
 
 0.500
SMOC2
SPARC related modular calcium binding 2.
   
  
 0.491
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.