node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CPSF1 | CPSF3 | ENSAMEP00000005940 | ENSAMEP00000008984 | Cleavage and polyadenylation specific factor 1. | Cleavage and polyadenylation specific factor 3. | 0.999 |
CPSF1 | CSTF2 | ENSAMEP00000005940 | ENSAMEP00000002242 | Cleavage and polyadenylation specific factor 1. | Cleavage stimulation factor subunit 2. | 0.977 |
CPSF1 | TUT1 | ENSAMEP00000005940 | ENSAMEP00000007096 | Cleavage and polyadenylation specific factor 1. | Speckle targeted PIP5K1A-regulated poly(A) polymerase; Poly(A) polymerase that creates the 3'-poly(A) tail of specific pre-mRNAs. Localizes to nuclear speckles together with PIP5K1A and mediates polyadenylation of a select set of mRNAs, such as HMOX1. In addition to polyadenylation, it is also required for the 3'-end cleavage of pre-mRNAs: binds to the 3'UTR of targeted pre-mRNAs and promotes the recruitment and assembly of the CPSF complex on the 3'UTR of pre-mRNAs. In addition to adenylyltransferase activity, also has uridylyltransferase activity. However, the ATP ratio is higher tha [...] | 0.675 |
CPSF3 | CPSF1 | ENSAMEP00000008984 | ENSAMEP00000005940 | Cleavage and polyadenylation specific factor 3. | Cleavage and polyadenylation specific factor 1. | 0.999 |
CPSF3 | CSTF2 | ENSAMEP00000008984 | ENSAMEP00000002242 | Cleavage and polyadenylation specific factor 3. | Cleavage stimulation factor subunit 2. | 0.979 |
CPSF3 | TUT1 | ENSAMEP00000008984 | ENSAMEP00000007096 | Cleavage and polyadenylation specific factor 3. | Speckle targeted PIP5K1A-regulated poly(A) polymerase; Poly(A) polymerase that creates the 3'-poly(A) tail of specific pre-mRNAs. Localizes to nuclear speckles together with PIP5K1A and mediates polyadenylation of a select set of mRNAs, such as HMOX1. In addition to polyadenylation, it is also required for the 3'-end cleavage of pre-mRNAs: binds to the 3'UTR of targeted pre-mRNAs and promotes the recruitment and assembly of the CPSF complex on the 3'UTR of pre-mRNAs. In addition to adenylyltransferase activity, also has uridylyltransferase activity. However, the ATP ratio is higher tha [...] | 0.680 |
CSTF2 | CPSF1 | ENSAMEP00000002242 | ENSAMEP00000005940 | Cleavage stimulation factor subunit 2. | Cleavage and polyadenylation specific factor 1. | 0.977 |
CSTF2 | CPSF3 | ENSAMEP00000002242 | ENSAMEP00000008984 | Cleavage stimulation factor subunit 2. | Cleavage and polyadenylation specific factor 3. | 0.979 |
CSTF2 | TUT1 | ENSAMEP00000002242 | ENSAMEP00000007096 | Cleavage stimulation factor subunit 2. | Speckle targeted PIP5K1A-regulated poly(A) polymerase; Poly(A) polymerase that creates the 3'-poly(A) tail of specific pre-mRNAs. Localizes to nuclear speckles together with PIP5K1A and mediates polyadenylation of a select set of mRNAs, such as HMOX1. In addition to polyadenylation, it is also required for the 3'-end cleavage of pre-mRNAs: binds to the 3'UTR of targeted pre-mRNAs and promotes the recruitment and assembly of the CPSF complex on the 3'UTR of pre-mRNAs. In addition to adenylyltransferase activity, also has uridylyltransferase activity. However, the ATP ratio is higher tha [...] | 0.687 |
DIS3 | NUDT15 | ENSAMEP00000013126 | ENSAMEP00000003940 | DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. | Nudix hydrolase 15. | 0.449 |
DIS3 | TUT1 | ENSAMEP00000013126 | ENSAMEP00000007096 | DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. | Speckle targeted PIP5K1A-regulated poly(A) polymerase; Poly(A) polymerase that creates the 3'-poly(A) tail of specific pre-mRNAs. Localizes to nuclear speckles together with PIP5K1A and mediates polyadenylation of a select set of mRNAs, such as HMOX1. In addition to polyadenylation, it is also required for the 3'-end cleavage of pre-mRNAs: binds to the 3'UTR of targeted pre-mRNAs and promotes the recruitment and assembly of the CPSF complex on the 3'UTR of pre-mRNAs. In addition to adenylyltransferase activity, also has uridylyltransferase activity. However, the ATP ratio is higher tha [...] | 0.556 |
DIS3 | XRN1 | ENSAMEP00000013126 | ENSAMEP00000013226 | DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. | 5'-3' exoribonuclease 1. | 0.804 |
NUDT15 | DIS3 | ENSAMEP00000003940 | ENSAMEP00000013126 | Nudix hydrolase 15. | DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. | 0.449 |
NUDT15 | TUT1 | ENSAMEP00000003940 | ENSAMEP00000007096 | Nudix hydrolase 15. | Speckle targeted PIP5K1A-regulated poly(A) polymerase; Poly(A) polymerase that creates the 3'-poly(A) tail of specific pre-mRNAs. Localizes to nuclear speckles together with PIP5K1A and mediates polyadenylation of a select set of mRNAs, such as HMOX1. In addition to polyadenylation, it is also required for the 3'-end cleavage of pre-mRNAs: binds to the 3'UTR of targeted pre-mRNAs and promotes the recruitment and assembly of the CPSF complex on the 3'UTR of pre-mRNAs. In addition to adenylyltransferase activity, also has uridylyltransferase activity. However, the ATP ratio is higher tha [...] | 0.745 |
NUDT15 | XRN1 | ENSAMEP00000003940 | ENSAMEP00000013226 | Nudix hydrolase 15. | 5'-3' exoribonuclease 1. | 0.679 |
PRPF4 | TUT1 | ENSAMEP00000013778 | ENSAMEP00000007096 | Pre-mRNA processing factor 4. | Speckle targeted PIP5K1A-regulated poly(A) polymerase; Poly(A) polymerase that creates the 3'-poly(A) tail of specific pre-mRNAs. Localizes to nuclear speckles together with PIP5K1A and mediates polyadenylation of a select set of mRNAs, such as HMOX1. In addition to polyadenylation, it is also required for the 3'-end cleavage of pre-mRNAs: binds to the 3'UTR of targeted pre-mRNAs and promotes the recruitment and assembly of the CPSF complex on the 3'UTR of pre-mRNAs. In addition to adenylyltransferase activity, also has uridylyltransferase activity. However, the ATP ratio is higher tha [...] | 0.557 |
PRPF4 | WBP4 | ENSAMEP00000013778 | ENSAMEP00000009139 | Pre-mRNA processing factor 4. | WW domain binding protein 4. | 0.860 |
RSPRY1 | TUT1 | ENSAMEP00000017876 | ENSAMEP00000007096 | Ring finger and SPRY domain containing 1. | Speckle targeted PIP5K1A-regulated poly(A) polymerase; Poly(A) polymerase that creates the 3'-poly(A) tail of specific pre-mRNAs. Localizes to nuclear speckles together with PIP5K1A and mediates polyadenylation of a select set of mRNAs, such as HMOX1. In addition to polyadenylation, it is also required for the 3'-end cleavage of pre-mRNAs: binds to the 3'UTR of targeted pre-mRNAs and promotes the recruitment and assembly of the CPSF complex on the 3'UTR of pre-mRNAs. In addition to adenylyltransferase activity, also has uridylyltransferase activity. However, the ATP ratio is higher tha [...] | 0.724 |
TUT1 | CPSF1 | ENSAMEP00000007096 | ENSAMEP00000005940 | Speckle targeted PIP5K1A-regulated poly(A) polymerase; Poly(A) polymerase that creates the 3'-poly(A) tail of specific pre-mRNAs. Localizes to nuclear speckles together with PIP5K1A and mediates polyadenylation of a select set of mRNAs, such as HMOX1. In addition to polyadenylation, it is also required for the 3'-end cleavage of pre-mRNAs: binds to the 3'UTR of targeted pre-mRNAs and promotes the recruitment and assembly of the CPSF complex on the 3'UTR of pre-mRNAs. In addition to adenylyltransferase activity, also has uridylyltransferase activity. However, the ATP ratio is higher tha [...] | Cleavage and polyadenylation specific factor 1. | 0.675 |
TUT1 | CPSF3 | ENSAMEP00000007096 | ENSAMEP00000008984 | Speckle targeted PIP5K1A-regulated poly(A) polymerase; Poly(A) polymerase that creates the 3'-poly(A) tail of specific pre-mRNAs. Localizes to nuclear speckles together with PIP5K1A and mediates polyadenylation of a select set of mRNAs, such as HMOX1. In addition to polyadenylation, it is also required for the 3'-end cleavage of pre-mRNAs: binds to the 3'UTR of targeted pre-mRNAs and promotes the recruitment and assembly of the CPSF complex on the 3'UTR of pre-mRNAs. In addition to adenylyltransferase activity, also has uridylyltransferase activity. However, the ATP ratio is higher tha [...] | Cleavage and polyadenylation specific factor 3. | 0.680 |