STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TRIM2Tripartite motif-containing protein 2; E3 ubiquitin-protein ligase that mediates the ubiquitination of phosphorylated BCL2L11. Also mediates the UBE2D1-dependent ubiquitination of NEFL. Plays a neuroprotective function. May play a role in neuronal rapid ischemic tolerance. (771 aa)    
Predicted Functional Partners:
TRIM44
Tripartite motif containing 44.
    
 
 0.765
UBB
Ubiquitin B.
   
 0.645
RPS27A
Ubiquitin-like domain-containing protein.
    
  0.606
UBE2D1
Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family.
   
  0.521
UBE2D2
Ubiquitin conjugating enzyme E2 D2; Belongs to the ubiquitin-conjugating enzyme family.
   
  0.521
RAI2
Retinoic acid induced 2.
    
 0.521
TRIM62
Tripartite motif containing 62.
   
  
0.520
TSNARE1
t-SNARE domain containing 1.
   
 
 0.519
TRIQK
Triple QxxK/R motif containing.
      
 0.482
FBXO2
F-box protein 2.
      
 0.482
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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