STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMAD3Mothers against decapentaplegic homolog. (414 aa)    
Predicted Functional Partners:
SMAD4
Mothers against decapentaplegic homolog.
   
0.999
SMAD2
Mothers against decapentaplegic homolog.
  
  
0.994
TGFBR1
Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.
   
 0.990
TGFBR2
Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
   
 0.983
ACVR1B
Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.
   
 0.981
ZFYVE9
Zinc finger FYVE domain-containing protein.
   
 0.980
E2F4
E2F transcription factor 4.
    
 0.978
M3YEF8_MUSPF
FOXO-TAD domain-containing protein.
    
 0.975
ZFYVE16
Zinc finger FYVE domain-containing protein.
   
 0.968
SMAD1
Mothers against decapentaplegic homolog.
  
 
0.966
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.