STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MEF2DMyocyte enhancer factor 2D (454 aa)    
Predicted Functional Partners:
NFATC4
Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
   
 0.927
NFATC2
Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
   
 0.925
NFATC1
Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
   
 
 0.916
CABIN1
Calcineurin binding protein 1
   
 0.913
EP300
E1A binding protein p300
   
 0.865
CREBBP
CREB binding protein
   
 0.854
MYOG
Myogenin (myogenic factor 4)
   
 0.832
MYOD1
Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation
   
 0.782
HDAC4
Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events
   
 0.755
MEF2B
Myocyte enhancer factor 2B
    
0.749
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9668
Other names: European polecat, M. putorius, Mustela putorius, Putorius putorius
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