node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATXN7L2 | ATXN7L3 | ENSMPUP00000003244 | ENSMPUP00000009402 | Ataxin 7 like 2. | Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...] | 0.850 |
ATXN7L2 | ENY2 | ENSMPUP00000003244 | ENSMPUP00000005825 | Ataxin 7 like 2. | Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...] | 0.888 |
ATXN7L2 | SUPT3H | ENSMPUP00000003244 | ENSMPUP00000012446 | Ataxin 7 like 2. | SPT3 homolog, SAGA and STAGA complex component. | 0.860 |
ATXN7L2 | SUPT7L | ENSMPUP00000003244 | ENSMPUP00000017882 | Ataxin 7 like 2. | SPT7 like, STAGA complex gamma subunit. | 0.620 |
ATXN7L2 | TADA3 | ENSMPUP00000003244 | ENSMPUP00000017016 | Ataxin 7 like 2. | Transcriptional adaptor 3. | 0.907 |
ATXN7L2 | TAF12 | ENSMPUP00000003244 | ENSMPUP00000015394 | Ataxin 7 like 2. | TATA-box binding protein associated factor 12. | 0.876 |
ATXN7L2 | TAF5L | ENSMPUP00000003244 | ENSMPUP00000012340 | Ataxin 7 like 2. | TATA-box binding protein associated factor 5 like. | 0.719 |
ATXN7L2 | TRRAP | ENSMPUP00000003244 | ENSMPUP00000016453 | Ataxin 7 like 2. | Transformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. | 0.956 |
ATXN7L2 | USP22 | ENSMPUP00000003244 | ENSMPUP00000000011 | Ataxin 7 like 2. | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. | 0.743 |
ATXN7L3 | ATXN7L2 | ENSMPUP00000009402 | ENSMPUP00000003244 | Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...] | Ataxin 7 like 2. | 0.850 |
ATXN7L3 | ENY2 | ENSMPUP00000009402 | ENSMPUP00000005825 | Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...] | Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...] | 0.972 |
ATXN7L3 | M3YZR7_MUSPF | ENSMPUP00000009402 | ENSMPUP00000016828 | Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...] | SCA7 domain-containing protein. | 0.896 |
ATXN7L3 | SUPT3H | ENSMPUP00000009402 | ENSMPUP00000012446 | Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...] | SPT3 homolog, SAGA and STAGA complex component. | 0.930 |
ATXN7L3 | SUPT7L | ENSMPUP00000009402 | ENSMPUP00000017882 | Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...] | SPT7 like, STAGA complex gamma subunit. | 0.857 |
ATXN7L3 | TADA3 | ENSMPUP00000009402 | ENSMPUP00000017016 | Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...] | Transcriptional adaptor 3. | 0.937 |
ATXN7L3 | TAF12 | ENSMPUP00000009402 | ENSMPUP00000015394 | Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...] | TATA-box binding protein associated factor 12. | 0.930 |
ATXN7L3 | TAF5L | ENSMPUP00000009402 | ENSMPUP00000012340 | Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...] | TATA-box binding protein associated factor 5 like. | 0.907 |
ATXN7L3 | TRRAP | ENSMPUP00000009402 | ENSMPUP00000016453 | Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...] | Transformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. | 0.907 |
ATXN7L3 | USP22 | ENSMPUP00000009402 | ENSMPUP00000000011 | Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...] | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. | 0.865 |
ENY2 | ATXN7L2 | ENSMPUP00000005825 | ENSMPUP00000003244 | Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...] | Ataxin 7 like 2. | 0.888 |