node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AR | PRKACA | ENSMPUP00000010444 | ENSMPUP00000003045 | Androgen receptor. | Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. | 0.940 |
AR | PRKACB | ENSMPUP00000010444 | ENSMPUP00000005718 | Androgen receptor. | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. | 0.940 |
AR | RUNX2 | ENSMPUP00000010444 | ENSMPUP00000012414 | Androgen receptor. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.897 |
AR | STUB1 | ENSMPUP00000010444 | ENSMPUP00000015850 | Androgen receptor. | STIP1 homology and U-box containing protein 1. | 0.640 |
BGLAP | BMP2 | ENSMPUP00000004593 | ENSMPUP00000006323 | Osteocalcin; Binds strongly to apatite and calcium. | Bone morphogenetic protein 2. | 0.766 |
BGLAP | RUNX2 | ENSMPUP00000004593 | ENSMPUP00000012414 | Osteocalcin; Binds strongly to apatite and calcium. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.868 |
BGLAP | SOX9 | ENSMPUP00000004593 | ENSMPUP00000014195 | Osteocalcin; Binds strongly to apatite and calcium. | SRY-box transcription factor 9. | 0.601 |
BMP2 | BGLAP | ENSMPUP00000006323 | ENSMPUP00000004593 | Bone morphogenetic protein 2. | Osteocalcin; Binds strongly to apatite and calcium. | 0.766 |
BMP2 | CBFB | ENSMPUP00000006323 | ENSMPUP00000005323 | Bone morphogenetic protein 2. | Core-binding factor subunit beta. | 0.410 |
BMP2 | RUNX2 | ENSMPUP00000006323 | ENSMPUP00000012414 | Bone morphogenetic protein 2. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.842 |
BMP2 | SOX9 | ENSMPUP00000006323 | ENSMPUP00000014195 | Bone morphogenetic protein 2. | SRY-box transcription factor 9. | 0.573 |
CBFB | BMP2 | ENSMPUP00000005323 | ENSMPUP00000006323 | Core-binding factor subunit beta. | Bone morphogenetic protein 2. | 0.410 |
CBFB | RUNX2 | ENSMPUP00000005323 | ENSMPUP00000012414 | Core-binding factor subunit beta. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.984 |
FOS | PRKACA | ENSMPUP00000009076 | ENSMPUP00000003045 | Fos proto-oncogene, AP-1 transcription factor subunit. | Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. | 0.930 |
FOS | PRKACB | ENSMPUP00000009076 | ENSMPUP00000005718 | Fos proto-oncogene, AP-1 transcription factor subunit. | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. | 0.930 |
FOS | RUNX2 | ENSMPUP00000009076 | ENSMPUP00000012414 | Fos proto-oncogene, AP-1 transcription factor subunit. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.941 |
PRKACA | AR | ENSMPUP00000003045 | ENSMPUP00000010444 | Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. | Androgen receptor. | 0.940 |
PRKACA | FOS | ENSMPUP00000003045 | ENSMPUP00000009076 | Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. | Fos proto-oncogene, AP-1 transcription factor subunit. | 0.930 |
PRKACA | PRKACB | ENSMPUP00000003045 | ENSMPUP00000005718 | Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. | 0.934 |
PRKACA | RUNX2 | ENSMPUP00000003045 | ENSMPUP00000012414 | Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.934 |