STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TLX3T cell leukemia homeobox 3. (338 aa)    
Predicted Functional Partners:
OLIG3
Oligodendrocyte transcription factor 3.
      
 0.801
LHX1
LIM homeobox 1.
    
 
 0.761
GRPR
Gastrin releasing peptide receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.734
PAX5
Paired box 5.
      
 0.665
PAX2
Paired box 2.
      
 0.665
LMX1A
LIM homeobox transcription factor 1 alpha.
    
 
 0.647
LMX1B
LIM homeobox transcription factor 1 beta.
    
 
 0.647
WDR4
tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family.
      
 0.622
PRDM13
PR/SET domain 13.
    
 
 0.528
LYL1
LYL1 basic helix-loop-helix family member.
      
 0.512
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.