STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EPN3Epsin 3. (635 aa)    
Predicted Functional Partners:
EPS15
Epidermal growth factor receptor pathway substrate 15.
   
 0.978
EPS15L1
Epidermal growth factor receptor pathway substrate 15 like 1.
   
 0.939
EPN2
Epsin 2.
  
 
 
0.934
ITSN2
Intersectin 2.
    
 0.914
EGFR
Receptor protein-tyrosine kinase.
    
 0.875
EPN1
Epsin 1.
  
 
 
0.874
HIP1R
Huntingtin interacting protein 1 related.
    
 
 0.860
PDGFRA
Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development.
    
  0.855
FGFR4
Fibroblast growth factor receptor.
    
  0.853
FGFR3
Fibroblast growth factor receptor.
    
  0.852
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.