node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APAF1 | BIRC2 | ENSMPUP00000011357 | ENSMPUP00000007131 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Baculoviral IAP repeat containing 2. | 0.703 |
APAF1 | BIRC3 | ENSMPUP00000011357 | ENSMPUP00000007139 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Baculoviral IAP repeat containing 3. | 0.703 |
APAF1 | CASP3 | ENSMPUP00000011357 | ENSMPUP00000010994 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Caspase 3; Belongs to the peptidase C14A family. | 0.993 |
APAF1 | CASP7 | ENSMPUP00000011357 | ENSMPUP00000001996 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Caspase 7; Belongs to the peptidase C14A family. | 0.897 |
APAF1 | CASP9 | ENSMPUP00000011357 | ENSMPUP00000016239 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Caspase 9; Belongs to the peptidase C14A family. | 0.999 |
APAF1 | M3XVS8_MUSPF | ENSMPUP00000011357 | ENSMPUP00000003178 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. | 0.992 |
APAF1 | M3Z4Y0_MUSPF | ENSMPUP00000011357 | ENSMPUP00000018642 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. | 0.999 |
APAF1 | XIAP | ENSMPUP00000011357 | ENSMPUP00000001342 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | X-linked inhibitor of apoptosis. | 0.846 |
BIRC2 | APAF1 | ENSMPUP00000007131 | ENSMPUP00000011357 | Baculoviral IAP repeat containing 2. | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | 0.703 |
BIRC2 | BIRC3 | ENSMPUP00000007131 | ENSMPUP00000007139 | Baculoviral IAP repeat containing 2. | Baculoviral IAP repeat containing 3. | 0.930 |
BIRC2 | CASP3 | ENSMPUP00000007131 | ENSMPUP00000010994 | Baculoviral IAP repeat containing 2. | Caspase 3; Belongs to the peptidase C14A family. | 0.966 |
BIRC2 | CASP7 | ENSMPUP00000007131 | ENSMPUP00000001996 | Baculoviral IAP repeat containing 2. | Caspase 7; Belongs to the peptidase C14A family. | 0.963 |
BIRC2 | CASP9 | ENSMPUP00000007131 | ENSMPUP00000016239 | Baculoviral IAP repeat containing 2. | Caspase 9; Belongs to the peptidase C14A family. | 0.973 |
BIRC2 | XIAP | ENSMPUP00000007131 | ENSMPUP00000001342 | Baculoviral IAP repeat containing 2. | X-linked inhibitor of apoptosis. | 0.965 |
BIRC3 | APAF1 | ENSMPUP00000007139 | ENSMPUP00000011357 | Baculoviral IAP repeat containing 3. | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | 0.703 |
BIRC3 | BIRC2 | ENSMPUP00000007139 | ENSMPUP00000007131 | Baculoviral IAP repeat containing 3. | Baculoviral IAP repeat containing 2. | 0.930 |
BIRC3 | CASP3 | ENSMPUP00000007139 | ENSMPUP00000010994 | Baculoviral IAP repeat containing 3. | Caspase 3; Belongs to the peptidase C14A family. | 0.964 |
BIRC3 | CASP7 | ENSMPUP00000007139 | ENSMPUP00000001996 | Baculoviral IAP repeat containing 3. | Caspase 7; Belongs to the peptidase C14A family. | 0.960 |
BIRC3 | CASP9 | ENSMPUP00000007139 | ENSMPUP00000016239 | Baculoviral IAP repeat containing 3. | Caspase 9; Belongs to the peptidase C14A family. | 0.971 |
BIRC3 | XIAP | ENSMPUP00000007139 | ENSMPUP00000001342 | Baculoviral IAP repeat containing 3. | X-linked inhibitor of apoptosis. | 0.962 |