STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity). (166 aa)    
Predicted Functional Partners:
IFNGR2
Interferon gamma receptor 2.
    
 0.998
IFNGR1
Interferon gamma receptor 1.
  
 
 0.991
IFNAR1
Interferon alpha and beta receptor subunit 1.
     
 0.982
JAK2
Tyrosine-protein kinase.
   
 
 0.982
JAK1
Tyrosine-protein kinase.
   
 
 0.981
M3XQ69_MUSPF
Uncharacterized protein.
  
 
 0.962
IFNB1
Interferon beta.
   
 
 0.960
PSME1
Proteasome activator subunit 1.
   
 
 0.957
IL21R
Interleukin 21 receptor.
   
 
 0.953
FOXP3
Forkhead box P3.
   
 0.948
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.