TMC6 protein (Mustela putorius) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

TMC6

Transmembrane channel-like protein. (748 aa)

Predicted Functional Partners:

EFHB

0.688

MRVI1

0.648

LRFN4

0.563

DUSP27

0.556

ZNF331

0.549

RCE1

0.532

GLRB

0.530

FAT2

0.530

VPS50

0.526

M3XM10_MUSPF

0.523

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DUSP27	EFHB	ENSMPUP00000015566	ENSMPUP00000013011	Dual specificity phosphatase 27, atypical; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	EF-hand domain family member B.	0.666
DUSP27	FAT2	ENSMPUP00000015566	ENSMPUP00000013571	Dual specificity phosphatase 27, atypical; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	FAT atypical cadherin 2.	0.514
DUSP27	GLRB	ENSMPUP00000015566	ENSMPUP00000005712	Dual specificity phosphatase 27, atypical; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Glycine receptor beta; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.523
DUSP27	LRFN4	ENSMPUP00000015566	ENSMPUP00000003563	Dual specificity phosphatase 27, atypical; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Leucine rich repeat and fibronectin type III domain containing 4.	0.671
DUSP27	M3XM10_MUSPF	ENSMPUP00000015566	ENSMPUP00000000110	Dual specificity phosphatase 27, atypical; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	ANK_REP_REGION domain-containing protein.	0.499
DUSP27	MRVI1	ENSMPUP00000015566	ENSMPUP00000012772	Dual specificity phosphatase 27, atypical; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Murine retrovirus integration site 1 homolog.	0.550
DUSP27	RCE1	ENSMPUP00000015566	ENSMPUP00000003475	Dual specificity phosphatase 27, atypical; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Ras converting CAAX endopeptidase 1.	0.527
DUSP27	TMC6	ENSMPUP00000015566	ENSMPUP00000013240	Dual specificity phosphatase 27, atypical; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Transmembrane channel-like protein.	0.556
DUSP27	ZNF331	ENSMPUP00000015566	ENSMPUP00000009821	Dual specificity phosphatase 27, atypical; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Zinc finger protein 331.	0.524
EFHB	DUSP27	ENSMPUP00000013011	ENSMPUP00000015566	EF-hand domain family member B.	Dual specificity phosphatase 27, atypical; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.666
EFHB	FAT2	ENSMPUP00000013011	ENSMPUP00000013571	EF-hand domain family member B.	FAT atypical cadherin 2.	0.533
EFHB	GLRB	ENSMPUP00000013011	ENSMPUP00000005712	EF-hand domain family member B.	Glycine receptor beta; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.633
EFHB	LRFN4	ENSMPUP00000013011	ENSMPUP00000003563	EF-hand domain family member B.	Leucine rich repeat and fibronectin type III domain containing 4.	0.662
EFHB	M3XM10_MUSPF	ENSMPUP00000013011	ENSMPUP00000000110	EF-hand domain family member B.	ANK_REP_REGION domain-containing protein.	0.582
EFHB	MRVI1	ENSMPUP00000013011	ENSMPUP00000012772	EF-hand domain family member B.	Murine retrovirus integration site 1 homolog.	0.636
EFHB	RCE1	ENSMPUP00000013011	ENSMPUP00000003475	EF-hand domain family member B.	Ras converting CAAX endopeptidase 1.	0.672
EFHB	TMC6	ENSMPUP00000013011	ENSMPUP00000013240	EF-hand domain family member B.	Transmembrane channel-like protein.	0.688
EFHB	ZNF331	ENSMPUP00000013011	ENSMPUP00000009821	EF-hand domain family member B.	Zinc finger protein 331.	0.526
FAT2	DUSP27	ENSMPUP00000013571	ENSMPUP00000015566	FAT atypical cadherin 2.	Dual specificity phosphatase 27, atypical; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.514
FAT2	EFHB	ENSMPUP00000013571	ENSMPUP00000013011	FAT atypical cadherin 2.	EF-hand domain family member B.	0.533