node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FN1 | PLAT | ENSMPUP00000007597 | ENSMPUP00000005702 | Fibronectin 1 | Plasminogen activator, tissue type | 0.729 |
FN1 | PLAU | ENSMPUP00000007597 | ENSMPUP00000003335 | Fibronectin 1 | Plasminogen activator, urokinase | 0.823 |
FN1 | PLAUR | ENSMPUP00000007597 | ENSMPUP00000006574 | Fibronectin 1 | Plasminogen activator, urokinase receptor | 0.875 |
FN1 | PLG | ENSMPUP00000007597 | ENSMPUP00000004597 | Fibronectin 1 | Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. | 0.857 |
FN1 | SERPINE1 | ENSMPUP00000007597 | ENSMPUP00000015759 | Fibronectin 1 | Serpin peptidase inhibitor, clade E, member 1; Belongs to the serpin family. | 0.798 |
FN1 | SERPINE2 | ENSMPUP00000007597 | ENSMPUP00000016588 | Fibronectin 1 | Serpin family E member 2; Belongs to the serpin family. | 0.591 |
FN1 | SMAD2 | ENSMPUP00000007597 | ENSMPUP00000000846 | Fibronectin 1 | Mothers against decapentaplegic homolog | 0.685 |
FN1 | SMAD7 | ENSMPUP00000007597 | ENSMPUP00000000838 | Fibronectin 1 | Mothers against decapentaplegic homolog | 0.490 |
FN1 | VTN | ENSMPUP00000007597 | ENSMPUP00000014197 | Fibronectin 1 | SMB domain-containing protein | 0.776 |
PLAT | FN1 | ENSMPUP00000005702 | ENSMPUP00000007597 | Plasminogen activator, tissue type | Fibronectin 1 | 0.729 |
PLAT | PLAU | ENSMPUP00000005702 | ENSMPUP00000003335 | Plasminogen activator, tissue type | Plasminogen activator, urokinase | 0.425 |
PLAT | PLAUR | ENSMPUP00000005702 | ENSMPUP00000006574 | Plasminogen activator, tissue type | Plasminogen activator, urokinase receptor | 0.689 |
PLAT | PLG | ENSMPUP00000005702 | ENSMPUP00000004597 | Plasminogen activator, tissue type | Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. | 0.849 |
PLAT | SERPINE1 | ENSMPUP00000005702 | ENSMPUP00000015759 | Plasminogen activator, tissue type | Serpin peptidase inhibitor, clade E, member 1; Belongs to the serpin family. | 0.993 |
PLAT | SERPINE2 | ENSMPUP00000005702 | ENSMPUP00000016588 | Plasminogen activator, tissue type | Serpin family E member 2; Belongs to the serpin family. | 0.958 |
PLAT | VTN | ENSMPUP00000005702 | ENSMPUP00000014197 | Plasminogen activator, tissue type | SMB domain-containing protein | 0.570 |
PLAU | FN1 | ENSMPUP00000003335 | ENSMPUP00000007597 | Plasminogen activator, urokinase | Fibronectin 1 | 0.823 |
PLAU | PLAT | ENSMPUP00000003335 | ENSMPUP00000005702 | Plasminogen activator, urokinase | Plasminogen activator, tissue type | 0.425 |
PLAU | PLAUR | ENSMPUP00000003335 | ENSMPUP00000006574 | Plasminogen activator, urokinase | Plasminogen activator, urokinase receptor | 0.998 |
PLAU | PLG | ENSMPUP00000003335 | ENSMPUP00000004597 | Plasminogen activator, urokinase | Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. | 0.762 |