STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAM53CFamily with sequence similarity 53 member C. (443 aa)    
Predicted Functional Partners:
EPB41
Erythrocyte membrane protein band 4.1.
      
 0.772
DYRK1A
Dual specificity tyrosine phosphorylation regulated kinase 1A.
    
 
 0.721
GMNN
Geminin DNA replication inhibitor.
      
 0.689
DYRK1B
Dual specificity tyrosine phosphorylation regulated kinase 1B.
    
 
 0.554
CREBL2
cAMP responsive element binding protein like 2.
      
 0.509
DCAF7
DDB1 and CUL4 associated factor 7.
    
 
 0.493
GLCCI1
Glucocorticoid induced 1.
   
  
 0.444
DNTTIP1
Deoxynucleotidyltransferase terminal interacting protein 1.
      
 0.442
FAM117B
Family with sequence similarity 117 member B.
   
  
 0.441
GTF2A2
Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family.
      
 0.438
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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