STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAX2Paired box 2 (452 aa)    
Predicted Functional Partners:
ETS1
ETS proto-oncogene 1, transcription factor; V-ets avian erythroblastosis virus E26 oncogene homolog 1
    
 
 0.856
ETS2
ETS proto-oncogene 2, transcription factor; V-ets avian erythroblastosis virus E26 oncogene homolog 2
    
 
 0.750
WNT1
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors
   
 
 0.691
EYA1
Eyes absent homolog; EYA transcriptional coactivator and phosphatase 1; Belongs to the HAD-like hydrolase superfamily. EYA family
    
 
 0.670
WT1
Wilms tumor 1
    
 
 0.669
OTX1
Orthodenticle homeobox 1
   
 
 0.653
SOX2
SRY-box 2; Felis catus SRY (sex determining region Y)-box 2 (SOX2), mRNA
   
 
 0.645
SIX2
SIX homeobox 2
   
 
 0.644
LHX1
LIM homeobox 1
   
 
 0.629
GBX1
Gastrulation brain homeobox 1
    
 
 0.610
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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