STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STEAP2STEAP2 metalloreductase. (490 aa)    
Predicted Functional Partners:
STEAP1
Ferric oxidoreductase domain-containing protein.
  
 
0.945
BNIP3L
BCL2 interacting protein 3 like.
    
 0.639
BNIP3
BCL2 interacting protein 3.
    
 0.545
CYB561
Cytochrome b561.
      
 0.535
ABCB8
ATP binding cassette subfamily B member 8.
   
  
 0.497
ABCB10
ATP binding cassette subfamily B member 10.
   
  
 0.464
TFRC
Transferrin receptor protein 1; Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Positively regulates T and B cell proliferation through iron uptake (By similarity); Belongs to the [...]
     
 0.450
LOC101080399
Uncharacterized protein; Belongs to the multicopper oxidase family.
   
  
 0.436
CP
Ceruloplasmin; Belongs to the multicopper oxidase family.
   
  
 0.436
NFS1
Aminotran_5 domain-containing protein.
      
 0.414
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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