STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAK4Non-specific serine/threonine protein kinase. (592 aa)    
Predicted Functional Partners:
CDC42-2
Uncharacterized protein.
   
 0.999
CDC42
Uncharacterized protein.
   
 0.991
INKA1
Inka box actin regulator 1.
    
 
 0.990
ITGB5
Integrin beta; Belongs to the integrin beta chain family.
   
 0.989
RAC2
Rac family small GTPase 2.
   
 0.959
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor 6.
    
 0.958
ARHGEF7
Rho guanine nucleotide exchange factor 7.
    
 0.958
NCK2
Cytoplasmic protein.
    
 0.956
LIMK1
LIM domain kinase 1.
    
0.944
LIMK2
LIM domain kinase 2.
    
0.939
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.