STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAGI2Membrane associated guanylate kinase, WW and PDZ domain containing 2. (1452 aa)    
Predicted Functional Partners:
CTNNB1
Catenin beta 1.
    
 0.951
RAPGEF2
Rap guanine nucleotide exchange factor 2.
    
 0.937
PTEN
Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.
    
 0.929
RAPGEF6
Uncharacterized protein.
    
 0.925
MAGI3
Membrane associated guanylate kinase, WW and PDZ domain containing 3.
  
 
0.913
MAGI1
Membrane associated guanylate kinase, WW and PDZ domain containing 1.
    
 
0.901
DDN
Dendrin.
    
 
 0.844
ZC3H12C
Zinc finger CCCH-type containing 12C.
   
  
 0.765
ZFAT
Zinc finger and AT-hook domain containing.
      
 0.751
KIDINS220
Kinase D interacting substrate 220.
    
   0.701
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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