STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAN2B1Lysosomal alpha-mannosidase; Necessary for the catabolism of N-linked carbohydrates released during glycoprotein turnover; Belongs to the glycosyl hydrolase 38 family. (1007 aa)    
Predicted Functional Partners:
MAN2C1
Mannosidase alpha class 2C member 1.
     
 0.953
CTBS
Chitobiase; Belongs to the glycosyl hydrolase 18 family.
      
 0.810
GUSB
Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family.
   
 
 0.706
FUCA1
Alpha-L-fucosidase 1.
    
 
 0.619
FUCA2
Alpha-L-fucosidase 2.
    
 
 0.603
MANBA
Mannosidase beta.
   
 
 0.575
ARSB
Arylsulfatase B; Removes sulfate groups from chondroitin-4-sulfate (C4S) and regulates its degradation (By similarity). Involved in the regulation of cell adhesion, cell migration and invasion in colonic epithelium (By similarity). In the central nervous system, is a regulator of neurite outgrowth and neuronal plasticity, acting through the control of sulfate glycosaminoglycans and neurocan levels (By similarity). Belongs to the sulfatase family.
   
 
 0.544
CCDC102A
Coiled-coil domain containing 102A.
      
 0.543
NAGLU
N-acetyl-alpha-glucosaminidase.
   
  
 0.527
GBA
Glucosylceramidase.
   
  
 0.523
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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